Milk fraud detection test

One-step immunochromatografic test for the detection of casein glycomacropeptide (cGMP) in milk.

Casein glycomacropeptide protein (cGMP) in milk is produced by the degradation of the casein present, due to the effect of enzymes or bacteria, which most often occurs during the cheese making process. In this process proteases are used, which specifically break down the casein and produce cGMP. Therefore, the amount in the whey of these cheeses is very high and the increased concentration in milk is usually an indication of milk adulteration with these cheese whey.

Other degradation processes (often related to the activity of bacteria present in dairy products) are also capable of increasing cGMP concentration, but not as dramatically.

5 minutes

High sensitivity

Easy to use

Reliable

Our products for the detection of milk adulteration

Product	Catalogue No.	Contents	Sample	CE Decl.
Stick cGMP	9.034.050.01.000	Stick 50 tests/kit (2 tubes; 25 test/tube). Visual reading	Milk	N/A
	9.034.005.15.000	Stick 5 tests/kit (individually pouched). Visual reading
	9.034.050.15.000	Stick 50 tests/kit (individually pouched). Visual reading

High specificity

High specificity through monoclonal antibodies: The product utilises monoclonal antibodies specific to casein glycomacropeptide (cGMP), ensuring that the detection of the adulteration marker is accurate and selective.

High sensitivity

The test is highly sensitive, capable of detecting levels of GMP that could indicate adulteration of 4 per cent cheese whey in milk. Indeed, if milking, storage, transport and processing conditions are optimal, this figure could be as low as 2 per cent or even 1 per cent.

Proven reliability

Reliability proven by correlation with standard methods (HPLC): the results from the test strips correlate and match those obtained by HPLC (high-performance liquid chromatography) using molecular exclusion columns, and are even rated as more reliable than other methodologies in certain contexts.

In fact, the product is used in academic research to carry out confirmatory qualitative identification following analysis by HPLC and mass spectrometry, which reinforces its technical credibility within the dairy industry.

Easy to use

Easy to use and visual recognition: It is described as a visual test that enables automatic qualitative recognition. The result is easily interpreted by the appearance of a red band on the strip, which simplifies the inspection process without requiring complex instrumentation for qualitative identification.

OPERON’s cGMP test strip has proven to be an effective tool in the fight against food fraud: by detecting cGMP – a marker found in high concentrations in serum but in very low concentrations in raw milk – it serves as an essential tool for producers, distributors and end buyers alike, enabling them to ensure the authenticity and quality of the milk in the face of illegal adulteration practices.

Publications

N.º	Title	Language
1	Estudio-de-evaluación-tecnica-del-kit-Stick-c-GMP	Spanish
2	Immunochromatographic-lateral-flow-test-strip-for-the-rapid-detection-of-added-bovine-rennet-whey-in-milk-and-milk-powder	English
3	Identification-of-glycomacropeptide-as-indicator-of-milk-and-dairy-drinks	English
4	Strip-test-for-the-detection-of-bovine-rennet-whey	English
5	Cheese Whey Milk Adulteration Determination Using Casein Glycomacropeptide as an Indicator by HPLC	English