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Tests for the detection of anti-gliadin and anti-human tissue transglutaminase antibodies.

One-step immunochromatographic tests for the detection of anti-gliadin and anti-human tissue transglutaminase antibodies in blood.

Celiac disease is a human enteropathy caused by a permanent intolerance to gluten and more specifically to its protein fraction called gliadin. The ingestion of this protein induces, in genetically predisposed individuals, a severe lesion of the intestinal mucosa characterised histologically by crypt hyperplasia with total or subtotal atrophy of the intestinal villi.

Due to the lack of a common symptomatology to facilitate diagnosis, as well as the high number of asymptomatic cases with intestinal deterioration, 85% of people with celiac disease are unaware of their gluten intolerance. This could lead to multiple and quite serious diseases, so the importance of early detection is vital to avoid major problems and allow the intestine to regenerate.

The Simple CD1WB test allows the detection in blood, plasma or serum of antibodies (IgA/IgG/IgM) directed against human tissue transglutaminase, the main autoantigen recognised by anti-endomysial antibodies. The Simple CD2WB test allows the detection of IgA anti-gliadin and anti-human tissue transglutaminase antibodies in blood and/or serum. The latter is especially indicated for paediatric patients under 16 years of age, and is available in authorised pharmacies.

≤10-15 minutes

Diet control

proteger 1

Simple and safe

Non-invasive

Cost-effective

lectura mediante scanner

Visual or automated reading

Our products for the detection of anti-gliadin and anti-human tissue transglutaminase antibodies.

Product
Catalogue No.
Contents
Sample
Promotional Sheet
CE Decl.
Instruct.
Simple CD1WB
9.028.020.00.000
Simple 20 tests/kit. Visual reading
Serum/Blood
Simple CD2WB
9.029.020.00.000
Simple 20 tests/kit. Visual or automated reading
Serum/Blood

Non-invasive procedure. Although the definitive diagnosis of celiac disease is based on characteristic histological changes observed in intestinal biopsies, serological tests, such as the detection of circulating anti-gliadin, anti-tTG and anti-endomysial antibodies, represent cheaper and less invasive testing methods for the detection of celiac disease.

Possibility of automated reading with OPERON immunochromatography strip reader. The interpretation of results in the Simple CD1WB and Simple CD2WB products can be done both visually and automated, thus minimising the possibility of error and allowing the recording and traceability of results.

Products adapted to rapid and urgent point-of-care or PoC diagnostics, with results in maximum 10-15 minutes, minimal handling and contact with the sample by the professional performing the test and with all components ready to use.

Monitoring of the gluten-free diet. The tests are also used to monitor adherence to the gluten-free diet, either because it is suspected that a gluten-contaminated food may have been ingested, or because it is desired to monitor more specifically those cases (especially children) whose diet is more difficult to control.

Publications

N.º
Title
Link
Language
1
Diagnostic screening for subclinical celiac disease using a rapid test in children aged 2–4
English
2
Immunochromatographic-Sticks-for-Tissue-Transglutaminase
English
3
Enfermedad celiaca: ¿diagnóstico a la cabecera del enfermo?
Spanish

Webinars

“Celiac condition. A new perspective for the determination and utility of its biomarkers”

An approach to celiac biomarkers given by Dr. Fabiola Fabiano, Clinical and laboratory immunologist and celiac disease specialist. 

The recorder webinar is available on demand. If you missed it, feel free to request it!

Webinar about celiac disease condition and the detection of its biomarkers taught by doctor Fabiola Fabiano
Contact us for more
information

    Frequently Asked Questions

    These tests are for professional use only, which means that they may only be performed by trained and qualified personnel.

    Both available tests, Simple CD1WB and Simple CD2WB, are qualitative tests.

    The Simple CD1WB and Simple CD2WB tests are compatible for fingerstick, venipuncture, serum and plasma samples.

    Our videos for the detection of anti-gliadin and anti-human tissue transglutaminase antibodies.