Celiac disease is a human enteropathy caused by a permanent intolerance to gluten and more specifically to its protein fraction called gliadin. The ingestion of this protein induces, in genetically predisposed individuals, a severe lesion of the intestinal mucosa characterised histologically by crypt hyperplasia with total or subtotal atrophy of the intestinal villi.
Due to the lack of a common symptomatology to facilitate diagnosis, as well as the high number of asymptomatic cases with intestinal deterioration, 85% of people with celiac disease are unaware of their gluten intolerance. This could lead to multiple and quite serious diseases, so the importance of early detection is vital to avoid major problems and allow the intestine to regenerate.
The Simple CD1WB test allows the detection in blood, plasma or serum of antibodies (IgA/IgG/IgM) directed against human tissue transglutaminase, the main autoantigen recognised by anti-endomysial antibodies. The Simple CD2WB test allows the detection of IgA anti-gliadin and anti-human tissue transglutaminase antibodies in blood and/or serum. The latter is especially indicated for paediatric patients under 16 years of age, and is available in authorised pharmacies.
Simple and safe
Visual or automated reading
“Celiac condition. A new perspective for the determination and utility of its biomarkers”
An approach to celiac biomarkers given by Dr. Fabiola Fabiano, Clinical and laboratory immunologist and celiac disease specialist.
The recorder webinar is available on demand. If you missed it, feel free to request it!
These tests are for professional use only, which means that they may only be performed by trained and qualified personnel.
Both available tests, Simple CD1WB and Simple CD2WB, are qualitative tests.
The Simple CD1WB and Simple CD2WB tests are compatible for fingerstick, venipuncture, serum and plasma samples.