Test for the semi-quantitative detection of human calprotectin

One-step immunochromatographic test kit for the semi-quantitative detection of human Calprotectin in faecal samples.

Inflammatory bowel disease (IBD), which comprises Crohn’s disease and Ulcerative Colitis, is a severe and incurable chronic disease of the intestinal tract. It affects around 2 million people across Europe, and its prevalence is increasing every day.

The symptoms of IBD closely resemble those of non-inflammatory diseases, such as irritable bowel syndrome. However, untreated IBD can cause serious problems for the patient, so a quick diagnosis to differentiate between the two diseases is crucial in these cases.

Currently, the gold standard technique is endoscopy, which is invasive for the patient, requires anaesthesia and is costly for the practitioner.

Calprotectin is recognised as a potential marker of intestinal mucosal inflammation, and offers a less invasive alternative. It is a hetero-complex with antimicrobial properties that is activated by neutrophils and, once released, can be detected in serum, body fluids and faeces. Several studies show that approximately 90% of patients with colorectal cancer also have increased levels of calprotectin.

10 minutes


proteger 1

Simple and safe

lectura mediante scanner

Automated reading

Our products for the semi-quantitative detection of human calprotectin

Catalogue No.
Promotional Sheet
CE Decl.
Simple Calprotectina
Simple 20 tests/kit. Visual or automated reading
Simple 5 tests/kit. Visual or automated reading
Positive Control (Calprotectina)
1 swab/kit

This test has a cut-off of 50 µg/g. Several publications point to this cut-off as the most suitable for differentiating between organic intestinal inflammation and functional bowel disease. In addition, it allows the use of stool samples stored at room temperature for up to 7 days without compromising test performance.

Possibility of automated reading with OPERON immunochromatography strip reader. The interpretation of results in the Simple Calprotectina product can be done both visually and automated, thus minimising the possibility of error and allowing the results to be recorded.

Products adapted to rapid and urgent point-of-care or POC diagnostics, with results in maximum 10 minutes, minimal handling and contact with the sample by the professional performing the test and with all components ready for use.

Controls are available to the user to validate the results obtained. They can be purchased as a commercial independent reference.


Effectiveness and Cost-Effectiveness of Calpro in Dx of IBD_2014
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    Frequently Asked Questions

    Stool samples can be stored refrigerated (+2-8°C) for up to 7 days. For prolonged storage, samples should be frozen at -20°C. Avoid subjecting the sample to successive freeze/thaw cycles.

    As indicated in the instructions for use, it is not recommended to use samples that have been collected in transport media or to which preservation agents (such as formalin, PBS, PVA or similar) or spiking agents have been added, as their presence may interfere with the test.

    If symptoms persist, other techniques are recommended. Both celiac disease and microscopic colitis polyps may present with inflammation.

    Normal levels of calprotectin in neonates can range from 22 to 860 µg/g, so it is not recommended to use this test in neonatal samples.

    In cases such as inflammatory bowel disease, colorectal cancer and other enteropathies, endoscopy and biopsy are also recommended to confirm the diagnosis obtained and to evaluate the degree of inflammation.