Tests for the differential detection of Influenza types A and B and Respiratory Syncytial virus, as well as SARS-COV-2 (COVID 19) and Respiratory Adenovirus

Immunochromatographic tests for the qualitative detection of Respiratory Syncytial Virus (RSV) and Influenza virus types A and B (in separate bands), as well as SARS-CoV-2 virus (COVID-19) and respiratory Adenovirus from respiratory swabs, washings and nasopharyngeal aspirates.

Respiratory Syncytial Virus (RSV) is the leading cause of emergency department visits and hospitalization for acute lower respiratory tract infections in infants and young children worldwide. In addition, its infective characteristics have made RSV one of the leading causes of nosocomial infection.

Influenza virus is a serious and highly contagious infection of the respiratory tract. Influenza type A viruses are generally more common than type B viruses and are also associated with the most severe influenza epidemics.

Adenovirus is a virus of the Adenoviridae family. The symptoms of Adenovirus infections are similar to a common cold, but unlike other respiratory viruses such as influenza or RSV, it is not seasonal and it can be detected throughout the year.

The SARS-CoV-2 coronavirus (causing COVID-19 disease) is associated with cases of pneumonia with frequent symptoms of dry cough, fever, fatigue or loss of smell, and can easily progress to severe pneumonia, severe acute respiratory syndrome, fatal multi-organ failure and even death.

The rapid identification of these viruses, which in many cases share the same symptoms, is very important as it saves on healthcare costs by reducing both the number of hospitalised patients and the drugs prescribed (if it is confirmed to be a viral infection, antibiotics would not be prescribed). In the case of influenza, not all antiviral drugs are effective against Influenza A virus and Influenza B virus. Hence the importance of distinguishing between the two types.

Results in maximum 15 minutes

Compatible with various samples

Simple and safe

Different formats and combinations adapted to different users

Automated reading

Our products for the differential detection of Influenza types A and B and Respiratory Syncytial virus, as well as SARS-COV-2 (COVID 19) and Respiratory Adenovirus

Product	Catalogue No.	Contents	Sample	Promotional Sheet
Simple/Stick RSV	9.064.020.15.000	Simple 20 tests/kit. Visual or automated reading	Nasal/Nasopharyngeal swab - Nasopharyngeal wash/aspirate
	9.064.020.46.000	Simple 20 tests/kit. Visual or automated reading
	9.064.020.71.000	Simple 20 tests/kit. Visual reading
	9.064.020.87.000	Simple 20 tests/kit + positive control. Visual or automated reading
Simple/Stick RespirAdeno	9.091.020.46.000	Simple 20 tests/kit. Visual or automated reading	Nasal/Nasopharyngeal swab - Nasopharyngeal wash/aspirate
	9.091.020.87.000	Simple 20 tests/kit + positive control. Visual or automated reading
	9.091.020.15.000	Stick 20 tests/kit. Visual reading
Simple/Stick Flu A+B	9.080.020.46.000	Simple 20 tests/kit. Visual or automated reading	Nasal/Nasopharyngeal swab - Nasopharyngeal wash/aspirate
	9.080.020.71.000	Simple 20 tests/kit. Visual reading
	9.080.020.87.000	Simple 20 tests/kit + positive control. Visual or automated reading
	9.080.020.15.000	Stick 20 tests/kit. Visual reading
Simple/Stick SARS-CoV-2	9.233.020.21.000	Simple 20 tests/kit. Visual or automated reading	Nasal/Oropharyngeal/Nasopharyngeal swab
	9.233.020.71.000	Simple 20 tests/kit. Visual reading
	9.233.020.87.000	Simple 20 tests/kit + positive control. Visual or automated reading
	9.233.020.15.000	Stick 20 tests/kit. Visual reading
Simpe RSV-Flu A+B	9.081.020.47.000	Simple 20 tests/kit. Visual or automated reading	Nasal/Nasopharyngeal swab - Nasopharyngeal wash/aspirate
	9.081.020.71.000	Simple 20 tests/kit. Visual reading
	9.081.020.87.000	Simple 20 tests/kit + positive control. Visual or automated reading
Simple RSV-Respiradeno	9.110.020.47.000	Simple 20 tests/kit. Visual or automated reading	Nasal/Nasopharyngeal swab - Nasopharyngeal wash/aspirate
	9.110.020.71.000	Simple 20 tests/kit. Visual reading
	9.110.020.87.000	Simple 20 tests/kit + positive control. Visual or automated reading
Simple Ag SARS-CoV-2 / Flu A+B	9.242.020.36.000	Simple 20 tests/kit. Visual or automated reading	Oropharyngeal/Nasopharyngeal swab
	9.242.020.71.000	Simple 20 tests/kit. Visual reading
	9.242.020.87.000	Simple 20 tests/kit + positive control. Visual or automated reading
Positive control (RSV/Flu/Adenovirus)	9.235.011.12.000	1 swab/kit	N/A	N/A
Positive control (SARS-CoV-2)	9.233.011.12.000	1 swab/kit	N/A	N/A

Feature 1

Rapid identification and differentiation of RSV, Influenza, SARS-CoV-2 and Respiratory Adenovirus allows for cost savings in healthcare, optimal patient management and the most appropriate diagnosis and treatment.

Feature 2

Products adapted to rapid and urgent point-of-care or PoC diagnostics, with reproducible results in 15 minutes maximum, without the need for volumetric measurements of reagents that are susceptible to error. In addition, they require minimal handling and contact with the sample by the professional performing the test, and come with all components ready for use.

Feature 3

Possibility of automated reading with OPERON immunochromatography strip reader. The interpretation of results on the Simple/Stick RSV, Simple/Stick Flu A+B, Simple/Stick RespirAdeno and Simple/Stick Ag SARS-CoV-2 products, as well as on any of the combos, can be done both visually and automated. This minimises the possibility of error and provides the professional in charge of the execution with the possibility of recording the results obtained.

Feature 4

We have references that include the swabs for sample collection, as well as a positive control so that the user can validate the results obtained. These controls can also be purchased as a separate commercial reference.

Publications

N.º	Title	Language
1	EVALUATION OF A RAPID IMMUNOCHROMATOGRAPHIC POINT OF CARE TEST THAT DETECTS THE RESPIRATORY SYNCYTIAL VIRUS IN HUMAN RESPIRATORY SAMPLES	English
2	EVALUATION OF A RAPID IMMUNOCHROMATOGRAPHIC POINT OF CARE TEST THAT DETECTS THE RESPIRATORY SYNCYTIAL VIRUS IN RESPIRATORY SAMPLES (POSTER FORMAT)	English
3	The impact of childhood RSV infection on children’s and parents’ quality of life: a prospective multicenter study in Spain	English

Webinars

“COVID-19, diagnostic tools”

Dr. María Alejandra Torres, haemato-oncologic and member of the Venezuelan COVID Commission, gives an interesting overview of all the diagnostic tools currently available for the detection of COVID-19.

The recorded webinar is available on demand. If you missed it, feel free to request it!

information

Frequently Asked Questions

Can several respiratory tests be performed on a single sample?

Our RSV, Flu A+B and SARS-CoV-2 detection products use the same dilution buffer. This means that, with a single sample, all three tests could be run and all three viruses could be detected.

Can tests be used as self-tests?

All tests are designed for use by healthcare professionals only.

Do the tests detect the different variants of SARS-CoV-2?

Both the Simple/Stick Ag SARS-CoV-2 test and the Simple Ag SARS-CoV-2/Flu A+B test use monoclonal antibodies specific to the N protein of the SARS-CoV-2 virus and are therefore suitable for detecting the different prevalent variants of the virus.

Does the diluent used for sample preparation inactivate SARS-CoV-2 virus?

Indeed, both tests are designed to be as safe as possible for the user. Both tests are designed to be as safe as possible for the professional who performs them, so the diluent contains virus-inactivating detergents.

What types of Influenza do these tests detect?

The tests detect the nucleoprotein of Influenza virus type A and type B, in separate bands.

What type of influenza is most common?

Influenza type A viruses are generally more frequent than type B viruses, and are associated with the most severe influenza epidemics (especially the H3N2 subtype), while type B infections are usually milder. Within type A, the H1N1 and H3N2 subtypes are the most important in humans.

Is H1N1 detected in the Stick/Simple Flu A+B test?

Influenza A viruses are generally more common than type B viruses. Within type A, the N1N1 subtypes are the most important in humans. The evaluation of the diagnostic sensitivity and specificity of our kit has not been done with samples characterised at subtype level. However, for the determination of the analytical sensitivity of Influenza type A we used a reference standard of the H1N1 subtype, so we can confirm that the Stick/Simple Flu A+B test detects the H1N1 influenza subtype.

What types of RSV do these tests detect?

The tests detect the F protein, which is responsible for fusion and entry of the virus into the cell. It is present in both subtypes of RSV (types A and B), and in all genotypes into which they are divided.

What types of Adenovirus do these tests detect?

The tests detect the Adenovirus hexon, which is a highly conserved protein in the various serotypes of the Adenovirus family. Types 3, 4, 7 and 14 are the most commonly associated with respiratory infection.

Is it possible to use means of transport with these samples?

The tests are compatible with different means of transport, which are indicated in the instructions for use of each product.

What kind of swabs can be used for sampling?

In general, we recommend Flocked Swabs from Copan Flock Technologies to ensure optimal test performance. In the Instructions for Use of each product, the swabs that have been evaluated and with which the best results are obtained are indicated. In addition, we have some references that include swabs.